Neanderthal Man (44 page)

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Authors: Svante Pbo

Tags: #In Search of Lost Genomes

BOOK: Neanderthal Man
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Kircher, Martin,
147
(fig.),
162
,
165

166
,
202

203
,
209

213
,
239
,
245

Klein, Richard,
190

Knauer, Felix,
56

Krapina Cave collection,
76

77
,
132

133

Krause, Johannes,
147
(fig.)

access to Vindija Cave remains,
133

134

background,
129

130

comparing Neanderthal mtDNA sequences with Denisova sequences,
229

233

DNA from Vindija Cave remains,
136

141

454 process,
117
,
119

Okladnikov Cave remains,
227

publishing the findings,
218

pyrosequencing,
114

sequencing the nuclear genome,
238

240

toasts,
234

235

 

Krings, Matthias,
1
,
8

12
,
16
,
18
,
21
,
74

76
,
78

79

Kučan, Željko,
138
,
139
(fig.)

Kudaravalli, Sridhar,
124

 

Lachmann, Michael,
170

Lalueza-Fox, Carles,
137

Lander, Eric,
164

166

Language development,
207
,
252

253

Language groups, sampling for genetic diversity,
93

Larhammar, Dan,
34

Lawrence Berkeley National Laboratory,
109

110
,
113

115
,
121

122

Leaky replacement,
248

Learning as human behavior,
206

207

Lenardic, Jadranka,
130

Lewin, Benjamin,
18

Limestone caves,
76

78

Lindahl, Tomas,
18
,
39

40
,
51

52
,
58
,
76

Lucy,
4

 

Magnolia latahensis,
56

57

Maillard reaction,
106

Major histocompatibility complex (MHC),
223

224

Malez, Mirko,
76

77
,
130

131

Mammoth remains

nuclear DNA extraction,
101

103
,
111

113

pyrosequencing,
115

SNPs,
173

tracing evolutionary history,
55

56

“Marco Polo Neanderthals”,
183

Maričić, Tomislav “Tomi,”
137

138
,
144

146
,
147
(fig.),
166
,
179

Marsupials.
See
Thylacinus cynocephalus

Matzke, Nicholas J.,
221

Max Planck Society,
81

90
,
120

121
,
155
,
202

203

McLean, Corey,
219

220

Melanesia,
245
,
247
,
249

252

Mengele, Josef,
81

82

Methyl groups,
148

Meyer, Matthias,
147
(fig.),
251

Mezmaiskaya Cave, Russia,
78

79
,
136

Middle East scenario,
189

191
,
195
,
197

200

Migration,
41

42
,
183

Mitochondria,
59

60

Mitochondrial DNA (mtDNA),
1

2
,
4

BYU data,
59

Croatian samples,
78

79

Denisova Cave remains,
228

231
,
240

244

determining Neanderthals’ contribution to the modern genome,
172

genetic variation among various Neanderthals,
95

97

human-ape link,
99

in animal droppings,
105

107

independent verification,
14

18

inheritance mechanism,
19

20

kangaroo rats,
42

43

limitations on view of genetic history,
19

20

Mitochondrial Eve,
14

multiregional model,
91

mutations,
12

14

Mylodon darwinii,
65

Native American remains,
71

Neanderthal type specimen and other Neanderthal specimens,
75

76

Neanderthal-modern human link,
96

98

 

nuclear DNA from mammoth bones,
101

103

Oetzi, the Ice Man,
69

70

Okladnikov Cave bone fragment,
228

PCR process,
8

12

quagga DNA,
34

reconstruction of Neanderthal mtDNA,
11
(fig.),
159

168

SNPs as indicators of interbreeding,
174

tracing a common ancestor,
13
(fig.)

Mitochondrial Eve,
13
(fig.),
14

15
,
88

Modern humans

cataloging genetic changes after Neanderthal-modern human separation,
209

213

cloning mummy DNA,
33

cognitive development,
205

207

common ancestor of apes and,
93
(fig.)

Denisova tooth morphology,
241

Denisovan genome and,
242

Denisovans, Neanderthals, and,
243

244
,
247

248

genome analysis of apes and,
219

Middle East scenario,
197

198

mtDNA comparisons with ancient DNA,
10
,
12

mtDNA variation,
75

76

potential for Neanderthal offspring,
200

203

replacement crowd,
198

200

technical development,
208

See also
Asians, modern; Europeans, modern

Molar, Neanderthal,
235
,
236
(fig.),
240

242
,
245

Molecular clock,
66

Monaco, Tony,
252

253

Monogamy,
212

Morphological features,
66
,
240

241
,
245

Mullikin, Jim,
173

174
,
183

Mullis, Kary,
8
,
37
,
39

40

Multiregional hypothesis of human origins,
20

21
,
91

98
,
188

189
,
220

Mummies

blue fluorescence in,
27

28
,
30
,
105

106

cartilage samples,
54

55

contamination of DNA data,
51

52

DNA extraction and cloning,
25

35

DNA survival and decay,
7

Native American remains,
68
,
71

Oetzi the Ice Man,
68

71

PCR process,
37

40

Mutations

cataloging genetic changes after Neanderthal-modern human separation,
209

213

derived alleles,
157

mapping convergent evolution,
66

Neanderthal contributions to modern European genome,
166

167

Neanderthal interbreeding with early modern humans,
192

obstacle to reconstructing genetic history,
12

14

putative dinosaur DNA,
59

60

studying nuclear DNA variation,
92

93

Myers, Gene,
111

Mylodon darwinii,
63

65
,
65
(fig.)

 

Native Americans

cannibalism,
131

Native Americans
(continued)

comparing modern genome with,
68
,
71

Denisovan genome and,
245

DNA data from preserved skeletons,
43

44

Nature Genetics
journal,
79
,
94

Nature
magazine,
18
,
51

52

contamination of data,
127
,
150

151
,
157

158
,
160

Denisova Cave findings,
236

238
,
242
,
248

249

DNA in amber,
58

DNA retrieval from animal droppings,
56

454 paper,
122

human-chimpanzee joining and separation,
170

mammoth data,
55

Mezmaiskaya Cave Neanderthal remains,
78

79

Neanderthal genome paper,
164

165

quagga data,
34

35
,
41

Siberian Neanderthal data,
228

thylacine data,
45

Nazi Germany,
81

83

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