Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (737 page)

   Prognosis assessment of multiple myeloma (as a tumor marker, it reflects burden of tumor cells).

   Evaluation of renal tubular disorders, index of GFR.

   CSF β
₂
-microglobulin levels have been used as a disease indicator of a variety of conditions, including multiple sclerosis, neuro-Behçet disease, sarcoidosis, AIDS–dementia complex, and meningeal metastases, especially meningeal dissemination of acute leukemia and malignant lymphoma.

   Interpretation

Increased In

   AIDS

   Aminoglycoside toxicity

   Amyloidosis

   Autoimmune disorders

   Breast cancer

   Crohn disease

   Felty syndrome

   Hepatitis

   Hepatoma

   Hyperthyroidism