Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (325 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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   Hairy cell leukemia
   Follicular, mantle cell, and splenic marginal zone lymphomas in leukemic phase
   Large granular lymphocytic leukemia (see p. 404)
   Secondary (Reactive) Lymphocytosis
   Infections (e.g., pertussis, infectious mononucleosis [EBV], infectious lymphocytosis [especially in children], infectious hepatitis, CMV, mumps, German measles, chickenpox, toxoplasmosis, babesiosis, chronic TB, cat scratch disease)
   Noninfectious causes (e.g., hypersensitivity reactions, stress)
   Drugs: efalizumab (Raptiva)
LYMPHOCYTOPENIA
   Definition

Lymphocytes are <1,600/μL (or <18%) in adults and <3,000/μL in children

   Causes
   Corticosteroid therapy or Cushing syndrome; epinephrine injection
   Certain infections (e.g., acute and chronic retroviral infections, TB)
   Sarcoidosis
   Congenital immunoglobulin disorders
   Chemotherapy and radiation therapy

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