Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1336 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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   Biopsies (lymph node, endometrium, fallopian tube, lung) may be taken. Place the biopsy specimen in a sterile container with the
Chlamydia
transport medium.
   Interpretation
   
Expected results:
No growth
   
Positive results:
Chlamydia
culture is very specific for infection caused by
C
.
trachomatis
.
   
Negative results:
Chlamydia
infection is not ruled out by a negative culture. Repeat testing, using a nucleic acid amplification test if appropriate for the site, is recommended for patients with a high suspicion for chlamydial infection.
   Limitations
   
Chlamydia
culture is intrinsically less sensitive than molecular diagnostic techniques.
Chlamydophila
species,
C
.
psittaci
, and
C
.
pneumoniae
, are not isolated by
C
.
trachomatis
culture. The following specimens are not recommended for
Chlamydia
culture:
   Peritoneal fluid
   Urethral discharge
   Urine
   Cul-de-sac fluid
   Vagina or vaginal fluid
   Throat

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