Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1208 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
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   Minimum specimen volume for analysis is 0.1 mL.
Suggested Reading
Dieudonné O, Godin PA, Van-Langendonckt A, et al. Biochemical analysis of the sperm and infertility.
Clin Chem Lab Med.
2001;39:455–457.
SEROTONIN, BLOOD
   Definition
   Serotonin is an indole amine synthesized by the cells of the intestinal mucosa. It is stored in and transported by platelets but also found in many body tissues, including the CNS. Serotonin acts as a vasoconstrictor and neurotransmitter; stimulant of smooth muscle contraction, prolactin release, and GH release; and functions in hemocoagulation. Other names: 5-hydroxytryptamine.
   
Normal range:
50–200 ng/mL.
   Use
   Confirming the diagnosis of carcinoid tumors.
   Adjunct test for 5-HIAA and chromogranin-A test to follow-up patients with carcinoid tumors.
   Interpretation

Increased In

   Metastasizing abdominal carcinoid tumors
   Dumpling syndrome
   Acute intestinal obstruction
   Cystic fibrosis
   AMI and nontropical sprue

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