Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1080 page)

TABLE 16–57. Normal Ranges for Müllerian-Inhibiting Substance

   Use

   Specific and sensitive marker for the presence of testicular tissue in boys with cryptorchidism.

   When measured either alone or in tandem with measurement of hCG-stimulated testosterone, MIS levels can be used to guide the treatment of these patients.

   Evaluation of the presence of any functioning testicular tissue in infants and children with ambiguous genitalia.

   Early detection of recurrence in patients with ovarian granulosa cell tumors.

   Assess the condition of PCO and premature ovarian failure.

   Assess ovarian reserve.

   Interpretation

Increased In

   PCOS (polycystic ovarian syndrome)

Decreased In

   Anorchia

   Abnormal or absence of testis

   Pseudohermaphroditism

   Syndrome of persistent müllerian ducts, despite the presence of structurally normal testes