Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis (1009 page)

BOOK: Wallach's Interpretation of Diagnostic Tests: Pathways to Arriving at a Clinical Diagnosis
12.94Mb size Format: txt, pdf, ePub
   Normal levels can occur in incomplete obstruction of the spinal canal.
   Increase in albumin alone can be a result of a lesion in the choroid plexus or a blockage in the flow of CSF.
   Determination of myelin basic protein in CSF may be of use in diagnosis of multiple sclerosis or other active demyelinating processes.
IMMUNOGLOBULIN M (IgM)
   Definition
   IgM is the first antibody to appear in response to antigen. It can be produced by the fetus and cannot be crossed by the placenta.
   
Normal range:
see Table 16.44.

TABLE 16–44. Normal Ranges for IgM by Age

   Use
   Diagnosis of hereditary and acquired IgM immunodeficiencies
   Diagnosis of Waldenström macroglobulinemia
   Earliest Ig serologic diagnosis of infectious disease
   Interpretation

Increased In

   Polyclonal
   Liver disease

Other books

Insipid by Brae, Christine
Fixed 01 - Fantasy Fix by Christine Warren
The Path of the Sword by Michaud, Remi
El Secreto de las Gemelas by Elisabetta Gnone
Captive by L. J. Smith
Regrets Only by Nancy Geary
Living With Regret by Lisa de Jong
The Fourth Protocol by Frederick Forsyth