The Lupus Book: A Guide for Patients and Their Families, Third Edition (53 page)

142–43;
autoimmune thyroiditis,
42;

apheresis,
234, 264

autoimmune vestibulitis,
123;
discovery of,

aplasia,
154

10;
and hormones,
128–29;
lupus as,
5

apoptosis,
37–38, 266

autonomic nervous system,
106, 113,
113

appearance of lupus patients,
195–96, 202, 204–

avascular necrosis,
83

5, 230, 232.
See also
skin

azathioprine,
140, 150, 226,
228,
243, 246

arnica,
187

aromatic amines,
43–44, 250

bacterial infections,
100, 137, 237

arterial blood gases,
86

Baker’s cyst,
80

arthralgia,
78

barium swallows,
134

arthritis,
78–84, 124.
See also
rheumatoid

basophils,
18,
19, 21

arthritis

behavioral issues,
106, 113–16, 120

Arthritis Foundation: information resources,
xi,

Behcet syndrome,
175

178, 257;
self-help courses,
195, 203;

benzodiazepines,
179

statistics on lupus,
11

beta-blockers,
53

arthroscopy,
80

beta carotene,
231

arylamine sulfas,
50, 240

beta globulins,
21

ascites,
137–38

betamethasone,
221,
222, 246, 247

aseptic meningitis,
105

bile ducts,
134

aseptic necrosis,
83

biliary tree,
139

Asians,
13, 256

bimodal survival curve,
259–60

aspirin: blood issues,
157, 164;
and drug-

biofeedback,
199, 204, 258

induced lupus,
54;
for inflammation,
207;

biologics,
264–65,
265

and pregnancy,
245;
research on,
262;
types,

biomarkers,
263

208

biopsies,
146–47,
147

assessment.
See
diagnosis and assessment

biphosphonate,
241,
241

Atabrine,
214–15

birth control,
50, 249–50

Index

[281]

black-and-blue marks,
75–76, 156

calcium supplements,
241

black cohosh,
187

calendula,
187

bladder,
144,
145,
150–51

Candida,
237

bleeding.
See
blood

capsicum,
187

blind spots,
218

carbamazepine,
53

blisters,
76

cardiolipin,
159

blood: anemia,
17, 65, 71, 152–55, 192;

cardiovascular system,
60, 95–96, 96–102,

bleeding,
118,
155–57;
blood pressure,
92–

223, 260

93, 102, 117, 194, 244, 260;
blood urea

carpal tunnel syndrome,
80, 81, 112

nitrogen (BUN),
146, 148;
chemistry panel,

casts,
146

65–66;
clotting problems,
155–57, 159–64,

Cataflam,
210

250, 260;
complex,
24;
components,
17–18,

cataracts,
122, 218

19, 21,
152;
hemoglobin,
152;
hemorrhages, catastrophic primary antiphospholipid

92, 138–39, 225, 234;
hyperviscosity,
68,

syndrome,
164

109,
118,
234;
malignancies,
173;
plasma, catnip,
187

17,
19, 21,
21–22,
24,
234;
platelets,
17,
19,

Caucasians,
13

21,
30, 31, 65, 157;
red blood cells

causes of lupus,
35–38.
See also
diagnosis and

(erythrocytes),
17,
19, 21,
30, 65;
testing,
65–

assessment

68, 118, 146.
See also
white blood cells

Cazenave, Pierre,
9

(leukocytes)

CD cells,
19,
20–21,
21

B lymphocytes (B cells): abnormalities,
36, 37;

Cell Cept,
246

and antibody production,
24,
27;
formation

cell signaling,
36

of,
19
;
and immune response,
18–20;
and

central nervous system (CNS),
104–20;

immunoglobulins,
25;
in inflammation

antibodies to,
30–31;
and behavioral

process,
26;
types,
21

changes,
113–16;
death of lupus patients,

bones,
78–84;
bone marrow,
19
;
bone

260;
diagnosing problems,
118–20;
drug

mineralization study,
240–41;
bone scans,

complications,
116–17;
historical of

171;
joints,
78–82,
79,
191;
in lupus

research,
104–5;
lupus syndromes of,
106–

patients,
83;
osteoporosis,
83, 231, 240–41,

13,
118
;
and steroids,
223;
symptoms in

258

lupus,
105–6;
unrelated abnormalities,
117

border clinics,
205–6

cerebral angiogram,
119

Bosentan,
93, 264

cerebral vasculitis,
118,
118

bowels,
136, 138–39

cerebrospinal fluid (CSF),
119

brain,
115, 119,
128

cervical spine,
81

breasts,
128

cevimeline,
126

breathing difficulty,
96

chamomilles,
187

British Isles Lupus Assessment Group

chemical factors in lupus,
43–45

(BILAG),
262

chemotherapy: action on lymphocytes,
233–34;

bromocriptine,
131, 231

anger associated with,
198;
early treatments,

bronchoalveolar lavage,
87

10;
and fertility,
243;
and fevers,
63;
future bronchoscopy,
87, 92

of,
261;
and GI problems,
136;
and

bruises,
75–76, 156

infections,
237;
and leukocytes,
155;
life

Budd-Chiari syndrome,
141

expectancy,
255;
and pregnancy,
244, 248;

budesonide,
220,
221

types,
225–27.
See also
therapeutic

bullous lupus,
70, 76, 232

approaches to lupus

burdock,
187

chest pain,
94–95

burning sensations,
113

chest x-rays,
85–86

bursae,
79,
80

chickweed,
188

butazolidin,
208–9

children with lupus,
92, 133, 156–57, 165–69,

butcher’s broom,
187

204–5.
See also
adolescents with lupus

butterfly rashes (malar rash),
9, 70, 73

Chinchon, Anna del,
214

chlorambucil,
226, 227,
228,
246

calamus,
187

chloroquine,
215, 216–17, 245

calcinosis,
81

cholesterol,
215

[282]

Index

chondritis,
123

cortisol,
127

chorea,
106

cortisone,
10, 218–25,
221,
245

chromosomes,
39

cortrosyn stimulation test,
224

chronic cutaneous lupus.
See
discoid lupus

costochondritis,
81

erythematosus (DLE)

counseling,
181, 203

chronic inflammatory demyelinating

cranberries,
188

polyneuropathy (CIDP),
111

cranial neuropathy,
121

Churg-Stauss granulomatosis vasculitis,
175

C-Reactive protein,
66, 238

circulating immune complexes,
31–32

creatine phosphokinase (CPK),
66, 97–98

circulating lymphocytes,
18

creatinine,
146, 148, 244

classification of lupus,
262

cricoarytenoid joint,
124

clinical activities indices,
262

Crohn’s disease,
137

clinical variables in lupus,
256

crossover syndrome,
7, 175

clofazimine,
232

cryoglobulin,
68

cluster-determined cells,
20

cryoglobulinemia,
109,
118,
234

cognitive dysfunction,
105, 111,
113,
113–15,

Cryptococcus,
117

118,
203

cutaneous lupus: acute,
70;
and cutaneous

cognitive therapy,
203–4, 258

vasculitis,
70, 75;
features of,
72–74;

colds,
46, 238

neonatal,
166, 249;
subacute cutaneous

collagen disease,
9

lupus erythematosus (SCLE),
41, 70, 71–72,

comfrey,
188

231.
See also
discoid lupus erythematosus

complete blood count (CBC),
65

(DLE)

complex (blood component),
24

cyclobenzaprine,
212, 246

complexity of lupus,
262

cyclophosphamide,
150, 225, 226,
228,
243,

computed tomography (CT) scan,
86, 119, 157–

246, 265–66

58

cyclosporin,
126, 150, 227,
228,
243, 264

conception,
243–44.
See also
fertility

cystitis, hemorrhagic,
225

conditioning,
186–91

cytoid bodies,
122

conduction deficits,
102

cytokines: and antibody production,
24
;
and

congenital heart block,
166–67, 249

biologics,
266;
and cognitive dysfunction,

congestive heart failure,
98–99

114;
and fatigue,
192;
and immune

conjunctivitis,
121

response,
20–22;
and infections,
237;
and

Conley, S. Lockard,
159

inflammation,
26;
and rheumatic disease,
22

connective tissues,
7

cytoplasm,
29–30

constipation,
136

cytotoxic cells,
25.
See also
natural killer cells

constitutional symptoms,
60, 62–63

Cytoxan,
117, 150, 225

constrictive pericarditis,
97

convulsions,
107

danazol,
231

cooking oils,
45

dandelion,
188

Coombs’ antibody,
68

dapsone,
232

coping with lupus,
195–201, 201–6.
See also

death of lupus patients,
259–60

treatments for lupus

definition of lupus,
5–9,
7

cornea,
125

deflazacort,
220,
221

coronary artery disease,
100–102

dehydroepiandrosterone (DHEA),
230

corticosteroids: adverse reactions,
117, 186,

delivery of health care,
256

258;
and antimalarials,
216;
for CNS

Denburg, Judith,
104–5

vasculitis,
108;
and cognitive dysfunction,

dendrite cells,
23

115;
and fibromyalgia,
178;
GI problems,

dental procedures,
100, 123–24, 238

136, 137, 140;
heart issues,
258;
and

deoxyribonucleic acid (DNA),
29, 43, 52, 69

infections,
237;
and pregnancy,
246;
and

depression,
200–201.
See also
psychiatric

renal function,
150;
research on,
264;
and

disorders

Sjo¨gren’s syndrome,
126

dermato/polymyositis,
7

corticotropin releasing hormone (CRH),
131,

devil’s claw,
188

200, 219–20

dexamethasone,
220,
221,
222

Index

[283]

diabetes mellitus,
50, 130–31

Dubois, Edmund,
10, 61

diagnosis and assessment: ACR criteria,
170,

Dubois’ Lupus Erythematosus
(Wallace and

262;
adolescents,
168;
autoantibodies,
27–