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Authors: Robin Cook

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“We expect to pay,” Daniel said.

There was another silence. Daniel felt a twinge of panic that the negotiations were not going well, raising the specter of losing the opportunity of using the Wingate Clinic for Butler's treatment. Considering the time constraints, such a loss could be the death knell for the project. Daniel sensed he had to offer more. Remembering Butler's assessment of Spencer and Paul's vanities, he gritted his teeth and said: “Then, down the road, after the FDA approves HTSR for general use, we could all coauthor a paper on the case.”

Daniel winced. The idea of coauthoring a paper with such bozos was a painful thought, even though he rationalized he could delay it indefinitely. But despite the offer, the silence persisted, and Daniel's panic grew. Remembering his own response to Butler's demand to use blood from the Shroud of Turin for the HTSR, he threw in that tidbit as well, explaining the patient had insisted on it. Daniel even proposed the same title he'd jokingly suggested to Stephanie.

“Now that sounds like one hell of a paper!” Paul responded suddenly. “I love it! Where would we publish it?”

“Wherever,” Daniel said vaguely. “
Science
or
Nature.
Wherever you'd like. I don't imagine it would be difficult to place.”

“Would HTSR work with blood from the Shroud of Turin?” Spencer asked. “As I recall, that thing is about five hundred years old.”

“How about around two thousand years old,” Paul said.

“Wasn't it proved to be a medieval forgery?” Spencer questioned.

“We're not going to get involved in argument about its authenticity,” Daniel said. “For our purposes, it doesn't matter. If the patient wants to believe it's real, it's fine with us.”

“But would it work, as a practical matter?” Spencer asked again.

“The DNA would be fragmented, whether it's five hundred
or two thousand years old,” Daniel said. “But that shouldn't be a problem. We only need fragments, which our HTSR probes will seek out after PCR amplification. We'll enzymatically patch together what we need for whole genes. It will work fine.”

“What about
The New England Journal of Medicine
?” Paul suggested. “That would be a coup for the clinic! I'd love to get something into that highfalutin publication.”

“Sure,” Daniel said, cringing at the idea. “Why not?”

“I'm beginning to like it too,” Spencer said. “That's the kind of article that would get picked up by the media like it was pure gold! It would be all over the newspapers. Hell, I can even see all the network anchors talking about it on the evening news.”

“I'm sure you're right,” Daniel said. “But remember, until the article comes out, there's got to be absolute secrecy about the whole affair.”

“We understand,” Spencer said.

“How are you going to get a sample from the Shroud of Turin?” Paul asked. “I understand the Catholic Church has it locked up in a kind of space-age vault over there in Italy.”

“We're looking into that as we speak,” Daniel said. “We have been promised high-level clerical assistance.”

“I'd think you'd have to know the Pope!” Paul commented.

“Perhaps we should talk about costs,” Daniel said, eager to change the subject now that the crisis had been averted. “We don't want any misunderstandings.”

“What kind of services are we talking about?” Paul asked.

“The patient we'll be treating has Parkinson's disease,” Daniel explained. “We will need a staffed OR and stereotaxic equipment for the implantation.”

“We have the OR,” Paul said. “But not stereotaxic equipment.”

“That's not a problem,” Spencer said. “We can borrow it from Princess Margaret Hospital. The Bahamian government and the medical community on the island have been very supportive of our relocation. I'm sure they will be happy to help. We just won't tell them what we're going to do with it.”

“We'll need the services of a neurosurgeon,” Daniel said. “One who is capable of being discreet.”

“I don't think that will be a problem either,” Spencer said. “There are several on the island who are, in my opinion, un-derutilized. I'm sure we could make arrangements with one of them. I don't know exactly how much he'd charge, but I can assure you, it will be a lot less than it would be in the States. My guess would be in the neighborhood of two or three hundred dollars.”

“You don't think the confidentiality issue will be problematic?” Daniel asked.

“I don't,” Spencer said. “They are all looking for work. With fewer tourists renting mopeds, head trauma has dropped off precipitously. I know, because two surgeons have come out to the clinic to leave their business cards.”

“Sounds serendipitous,” Daniel said. “Other than that, all we need is space in your lab. I assume you have a lab to do your reproductive work.”

“You will be amazed at our lab,” Paul said proudly. “It is state-of-the-art and a lot more than just an infertility lab! And in addition to myself, we have several talented technicians at your disposal who are experienced at nuclear transfer and who are eager to learn HTSR.”

“We won't need the assistance of any lab personnel,” Daniel said. “We'll do our own cellular work. What we do need are human oocytes. Is it possible for you to supply them?”

“Of course!” Paul said. “Oocytes are our specialty and soon to be our bread and butter. We're intending to supply them for all of North America in the future. What is your time frame?”

“As soon as possible,” Daniel said. “This might sound overly optimistic, but we'd like to be ready to implant in a month. We're under a time constraint, with a short window of opportunity imposed by the patient volunteer.”

“No problem on this end,” Paul said. “We can supply you with oocytes tomorrow!”

“Really?” Daniel questioned. It seemed too good to be true.

“We can get you oocytes whenever you want,” Paul said. Then he added with a laugh, “Even on holidays!”

“I'm impressed,” Daniel said sincerely. “And relieved. I
was worried that procuring oocytes might hold us up. But that brings us back to costs.”

“Except for the oocytes, we have no experience what to charge,” Spencer said. “To tell you the truth, we never anticipated someone using our clinic. Let's make it simple: How about twenty thousand for using the operating room, including its staff, and twenty thousand for the lab flat rate.”

“Fine,” Daniel said. “What about the oocytes?”

“Five hundred a pop,” Paul said. “And we guarantee at least five divisions with each one or we replace it.”

“That sounds fair,” Daniel said. “But they have to be fresh!”

“They will be as fresh as a daisy,” Paul said. “When can we expect you?”

“I'll get back to you either later today or tonight,” Daniel said. “Or, at the latest, by tomorrow. We really have to get moving on this.”

“We'll be here,” Spencer said.

Daniel slowly replaced the telephone receiver. When it was safely in its cradle, he let out a whoop. He had a strong feeling, despite the recent setbacks, that CURE, HTSR, and his own destiny were back on track!

 

Dr. Spencer Wingate had left his tanned hand on the telephone receiver after hanging up while his mind mulled over the conversation he'd just had with Dr. Daniel Lowell. It had not gone as he'd imagined or hoped, and he was disappointed. When the issue of the famous researcher wanting to use the Wingate Clinic had unexpectedly surfaced two weeks previously, he'd thought it providential since they'd just opened their doors after eight months of construction and confusion. In his mind, a professional association with a man who Paul said might win a Nobel Prize would have been a superb way to announce to the world that the Wingate was back in business after the regrettable fracas in Massachusetts the previous May. But as things stood, there could be no announcement. Forty thousand dollars might be nice, but it was a mere pittance in comparison to the money they had just spent getting the clinic built and equipped.

Spencer's office door, which had been slightly ajar from
when Spencer had recently rushed back in from locating his second-in-command, was pushed open to its full extent. Filling the doorway was Dr. Paul Saunders's short, square frame. A broad smile displayed his equally square, widely spaced teeth. He obviously did not share Spencer's disappointment.

“Can you imagine?” Paul blurted. “We're going to have a paper in the
New England Journal of Medicine
!” He threw himself into a chair facing Spencer's desk and punched the air with upraised fists like he'd just won a stage of the Tour de France. “And what a paper: ‘The Wingate Clinic, the Shroud of Turin, and HTSR Combine for the First Cure of Parkinson's Disease.' It's going to be fantastic! People will be beating a path to our door!”

Spencer leaned back and put his hands with fingers intertwined behind his head. He regarded the head of research, a title Paul had insisted upon, with a degree of condescension. Paul was a hard worker with vision, but he could be overly enthusiastic, and he lacked the practicality necessary to run a business properly. In the clinic's previous incarnation in Massachusetts, he'd practically run it into the ground financially. Had Spencer not mortgaged the clinic to the hilt and socked away most of the clinic's assets offshore, they wouldn't have survived.

“What makes you so sure there will be a paper?” Spencer asked.

Paul's face clouded over. “What are you talking about? We just discussed it on the phone, title and all, with Daniel. He's the one who suggested it.”

“He suggested it, but how can we be sure it will happen? I agree, it would be great if it did, but he could just put it off indefinitely.”

“Why the hell would he do that?”

“I don't know, but for some reason secrecy's high on his list, and a paper would destroy that. He's not going to want to write a paper, at least not soon enough for us, and if we went ahead and did it without him, he'd probably just deny any involvement in the case. If that happened, no one would publish it.”

“You've got a point,” Paul agreed.

The two men eyed each other across the expanse of
Spencer's desk. A jet on its final approach to Nassau International Airport thundered overhead. The clinic was sited just west of the airport, on dry, scrubby land. It was the only place they could reasonably buy adequate acreage and fence it in appropriately.

“Do you think he was being straight about using the Shroud of Turin?” Paul asked.

“I don't know that either,” Spencer said. “It sounds a bit fishy to me, if you know what I mean.”

“On the contrary, the concept sounded intriguing to me.”

“Don't get me wrong,” Spencer said. “The idea is interesting and certainly would make a damn good scientific paper and international news story, but when you put it all together, including the secrecy issue, there's something decidedly dubious involved. I mean, did you buy his explanation when you asked him why he was going to all this trouble?”

“You mean about his wanting to prove HTSR to himself?”

“Precisely.”

“Not completely, although it is true that the U.S. Congress is thinking of banning HTSR. And now that you've got me thinking, he did accept the fees you suggested a bit too quickly, as if the price didn't matter.”

“I couldn't agree more,” Spencer said. “I had no idea how much to ask to use our facilities, and I just pulled some figures out of the air and expected him to come back with a counteroffer. Hell, I should have asked for twice as much, as quickly as he agreed.”

“So, what is your take?”

“I think the identity of the patient is the issue,” Spencer said. “That's the only thing that comes to mind that makes sense.”

“Like who?”

“I don't know,” Spencer said. “But if I were forced to guess, my first thought would be a family member. My second guess would be someone wealthy, someone very wealthy and possibly famous and wealthy, which is where I'd put my money!”

“Wealthy!” Paul repeated. A slight smile appeared on his face. “A cure could be worth millions.”

“Exactly, which is why I think we should proceed with the
rich-and-famous hypothesis. After all, why should Daniel Lowell potentially get millions while we get a paltry forty thousand!”

“Which means we have to find out the identity of this patient volunteer.”

“I was hoping you'd see this affair from my perspective. I was afraid you might feel it was worth it just to work with this renowned researcher.”

“Hell, no!” Paul snapped. “Not when we can't get the promotional benefits we expected. He's even implied we're not going to get hands-on instruction in HTSR when he said he'd be doing his own cellular work. Originally, I thought that was a given. I still want to learn the procedure, though, so when he calls back, mention that that has to be part of the package.”

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