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See Also (Topic, Algorithm, Electronic Media Element)
Central Retinal Artery Occlusion (CRVA)
Central Retinal Venous Occlusion (CRVO)
Retinal Detachment
Visual Loss
CODES ICD9
250.50 Diabetes with ophthalmic manifestations, type II or unspecified type, not stated as uncontrolled
362.16 Retinal neovascularization NOS
379.23 Vitreous hemorrhage
ICD10
E13.39 Oth diabetes mellitus w oth diabetic ophthalmic complication
Axial twist of a portion of the GI tract around its mesentery causing partial or complete obstruction of the bowel
Often associated with other GI abnormalities
In pediatric setting, infants typically involved:
Abnormal embryonic development
Can be precipitated by pathologic distention of the colon
Blood supply may be compromised by venous congestion and eventual arterial inflow obstruction, leading to gangrene of the bowel and potential infarction
ETIOLOGY
3rd most common cause of colonic obstruction (10–15%) following tumor and diverticular disease
Epidemiology:
0–1 yo: 30%
1–18 yo: 20%
Over 18 yo: 50%
Often associated with other GI abnormalities
Cecum (52%):
More common in young adults, < 50 yr old
Due to improper congenital fusion of the mesentery with the posterior parietal peritoneum, causing the cecum to be freely mobile in varying degrees
Associated with increased gas production (malabsorption and pseudo-obstruction)
Can be seen in pregnancy and after colonoscopy
Sigmoid (43%):
More common in:
Elderly
Institutionalized
Chronic bowel motility disorders (Parkinson)
Psychiatric diseases (schizophrenia)
Due to redundant sigmoid colon with narrow mesenteric attachment
Associated with chronic constipation and concomitant laxative use
Transverse colon and splenic flexure (5%)
Gastric volvulus (rare) associated with diaphragmatic defects
Pediatric Considerations
Midgut volvulus:
Due to congenital malrotation in which the midgut fails to rotate properly in utero as it enters the abdomen
Entire midgut from the descending duodenum to the transverse colon rotates around its mesenteric stalk, including the superior mesenteric artery
Common in neonates (80% <1 mo old, often in 1st week; 6–20% >1 yr old)
Males > females, 2:1
Sudden onset of bilious emesis (97%) with abdominal pain
May have previous episodes of feeding problems/bilious emesis
In children >1 yr old, associated with failure to thrive, alleged intolerance to feedings, chronic intermittent vomiting, bloody diarrhea
Constipation
Mild distention, since obstruction higher in GI tract
May not appear toxic based on degree of ischemia
DIAGNOSIS SIGNS AND SYMPTOMS History
Infants: Vomiting in 90%:
May be bilious
Older children and adults: Variable and often insidious:
80% with chronic symptoms; weeks to months to years
Bowel obstruction secondary to volvulus:
Colicky, cramping abdominal pain (90%)
Abdominal distention (80%)
Obstipation (60%)
Nausea and vomiting (28%)
Cecal volvulus:
Highly variable; intermittent episodes to sudden onset of pain and distention
Sigmoid volvulus:
Vomiting uncommon
More insidious onset
Abdominal pain/distention, nausea, and constipation
Gastric volvulus:
Triad of Borchardt: Severe epigastric distension, intractable retching, inability to pass nasogastric tube (30% of patients)
Physical-Exam
Presence of gangrenous bowel:
Increased pain
Peritoneal signs: Guarding, rebound, and rigidity
Fever
Blood on digital rectal exam
Tachycardia and hypovolemia
Cecal volvulus:
Distended abdomen
Often a palpable mass in the left upper quadrant/midabdomen
Pediatric Considerations
Child will appear well with normal exam early in clinical course
70% present with chronic symptoms
40% of neonates with bilious vomiting will require a surgical intervention
Hematochezia, abdominal distention or pain, and shock indicate ischemia/necrosis
ESSENTIAL WORKUP
CBC, BMP, UA
Plain abdominal radiograph
Upper GI series (best initial exam for children)
CT abdomen/pelvis with IV contrast (optimal for adults)
Barium enema
US
DIAGNOSIS TESTS & NTERPRETATION Lab
May give clues as to the presence of gangrenous bowel, but normal lab values do not exclude the diagnosis
CBC:
Leukocytosis (WBC >20,000) suggests strangulation with infection/peritonitis.
Electrolytes, BUN, creatinine, glucose:
Anion gap acidosis due to lactic acidosis
Prerenal azotemia due to dehydration
Urinalysis:
Elevated specific gravity and ketones
Imaging
Plain abdominal radiograph:
Suggestive but often inconclusive
Diagnostic finding present in <70% of cases
Sigmoid volvulus: Inverted U-shaped loop of dilated colon arising from the pelvis
Cecal volvulus—dilated and displaced:
Cecum in the left abdomen (kidney shaped), often with dilated loops of small bowel
CT scan:
“Whirl” sign in cecal volvulus
May be useful in sigmoid volvulus to determine extent of obstruction
Upper GI series (best for duodenum, but operator dependent):
Abrupt ending or corkscrew tapering of contrast seen (75%)
Subtle findings (25%)
Barium enema:
“Bird’s beak” deformity at the site of torsion
Perform cautiously because of perforation risk
Beware of false positives with infants who normally have inadequately fixed cecums
US (specific but not sensitive):
Abnormal position of the superior mesenteric vein (anterior or left of SMA)
“Whirlpool” sign of volvulus: Vessels twirled around the base of the mesentery
3rd part of duodenum not in normal retromesenteric position (between mesenteric artery and aorta)
Pediatric Considerations
Diagnosis of midgut volvulus:
Duodenum lies entirely to the right of the spine on plain films
“Double-bubble” sign on an upright film due to distended stomach and proximal duodenal loop
Established by upper GI swallow: Coiled spring/corkscrew appearance of jejunum in the right upper quadrant
Plain x-ray normal or equivocal in 20% of cases
ALERT
Evaluate any child with signs/symptoms of obstruction (including bilious vomiting and abdominal pain) for malrotation, even if he or she appears nontoxic
Delay in diagnosis >1–2 hr results in gangrenous bowel, necessitating large resection and leading to permanent parenteral nutrition with its associated complications