Rosen & Barkin's 5-Minute Emergency Medicine Consult (502 page)

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Authors: Jeffrey J. Schaider,Adam Z. Barkin,Roger M. Barkin,Philip Shayne,Richard E. Wolfe,Stephen R. Hayden,Peter Rosen

Tags: #Medical, #Emergency Medicine

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RISK FACTORS

Adnexal torsion:

  • Reproductive-age women
  • Ovarian cysts, especially >5 cm
  • Ovarian hyperstimulation
  • Tumors: Serous cystadenoma most common; teratomas
  • Pelvic surgery: Tubal ligation; hysterectomy
  • Pregnancy
  • History of pelvic inflammatory disease
Pregnancy Considerations

Torsion in pregnancy usually occurs in the 1st trimester, and in vitro fertilization or ovarian induction are risk factors.

Pediatric Considerations

15% of adnexal torsions occur in children

ALERT
  • Anticoagulated patients at increased risk of:
    • Hemorrhagic corpus luteal cyst
    • Significant bleed from ruptured cyst, including with ovulation
ETIOLOGY
  • Ovarian cyst:
    • Follicular cysts result from nonrupture of mature follicle or failure of atresia of immature follicle
    • Corpus luteal cysts result from unrestrained growth in early pregnancy or from normal intracystic hemorrhage days after ovulation
    • Other cysts:
      • Theca lutein
      • Cystic teratoma
      • Endometrioma (chocolate cyst)
  • Adnexal torsion:
    • Right > left
    • Highest frequency in reproductive women
ALERT

Cysts found in postmenopausal women suggest carcinoma

DIAGNOSIS
SIGNS AND SYMPTOMS
History
  • Ovarian cyst:
    • Abdominal pain
      • Sharp, unilateral
      • Intermittent vs. constant
      • Migration
      • Previous episodes
      • May occur with exercise, intercourse, trauma, or pelvic exam
    • Fever is rare
    • Irregular menses (may suggest polycystic ovary syndrome)
    • Infertility
    • Pregnancy status
    • Previous STDs
    • History of breast or GI cancer (may metastasize)
  • Adnexal torsion:
    • Variable history
    • Abdominal pain:
      • Sudden, sharp, colicky
      • Localized vs. diffuse
      • Referred pain to groin or flank
      • May be chronic or recurring with torsion/detorsion
    • Fever
    • Nausea/vomiting
    • Vaginal bleeding
    • UTI symptoms
Physical-Exam
  • Ovarian cyst:
    • Abdominal tenderness (mild to severe with peritonitis)
    • Adnexal tenderness
    • Pelvic mass
    • Hemorrhagic shock possible:
      • Usually from corpus luteal cyst rupture
      • Orthostasis, hypotension, tachycardia
  • Adnexal torsion:
    • Abdominal tenderness (mild to severe)
    • Adnexal tenderness
    • Adnexal mass
ESSENTIAL WORKUP
  • Pregnancy test essential to rule out ectopic pregnancy
  • Rapid hemoglobin or hematocrit
DIAGNOSIS TESTS & NTERPRETATION
Lab
  • Urine or serum human chorionic gonadotropin determination
  • CBC
  • Urinalysis
  • If significant hemorrhage, type and cross packed RBCs
  • Cervical cultures to rule out PID
Imaging
  • Transvaginal US:
    • Adnexal cysts and masses:
      • Cystic masses <5 cm in premenopausal women generally benign
      • Should be re-evaluated at the end of menstruation
    • Pelvic free fluid
    • Enlarged, edematous ovary (suggests torsion)
  • Doppler:
    • May show decreased flow with torsion
    • Important to document normal blood flow on Doppler in ED, even though does not rule out recent torsion of ovary
  • MRI:
    • Consider in pregnant patients with right lower quadrant pain and nondiagnostic US and Doppler
  • CT:
    • May demonstrate cysts or evidence of torsion or suggest alternative diagnosis
    • May provide enough information to proceed to laparoscopy if abnormal ovary and no other cause of pain identified
    • Uterus may be shifted to side of torsed adnexa
    • Ascites may be present
ALERT

US sensitivity for diagnosis of ovarian torsion is not well established; continue workup if high clinical suspicion

Diagnostic Procedures/Surgery
  • Culdocentesis:
    • No longer commonly done
    • May yield serosanguinous fluid with ruptured cyst
    • Hematocrit >15% suggests significant hemoperitoneum
  • Laparoscopy is gold standard for torsed adnexa and definitive diagnosis
Pediatric Considerations
  • Early detorsion of adnexa by laparoscopy is now advocated to preserve ovarian function
  • Followed by frequent follow-up visits to monitor for malignancy
DIFFERENTIAL DIAGNOSIS
  • Ectopic pregnancy
  • PID
  • Round ligament pain
  • Endometriosis
  • Neoplasm
  • Torsion of uterus
  • Appendicitis
FOLLOW-UP RECOMMENDATIONS

Ovarian cyst

  • If pain is resolved and cyst is <4–5 cm, close follow-up is recommended with gynecology for further studies
PEARLS AND PITFALLS

Adnexal torsion:

  • Torsion is a clinical diagnosis:
    • US may show flow to an ovary that has detorsed
  • Symptoms can be varied and nonspecific
  • Always include adnexal torsion in differential of abdominal pain
ADDITIONAL READING
  • Becker JH, de Graaff J, Vos CM. Torsion of the ovary: A known but frequently missed diagnosis.
    Eur J Emerg Med
    . 2009;16:124–126.
  • Bottomley C, Bourne T. Diagnosis and management of ovarian cyst accidents.
    Best Pract Res Clin Obstet Gynaecol
    . 2009;23:711–724.
  • Chang HC, Bhatt S, Dogra VS. Pearls and pitfalls in diagnosis of ovarian torsion.
    Radiographics.
    2008;28:1355–1368.
  • Houry D, Abbott JT. Ovarian torsion: A fifteen-year review.
    Ann Emerg Med
    . 2001;38:156–159.
  • McWilliams GD, Hill MJ, Dietrich CS 3rd. Gynecologic emergencies.
    Surg Clin North Am
    . 2008;88:265–283.
  • Moore C, Meyers AB, Capostato J, et al. Prevalence of abnormal CT findings in patients with proven ovarian torsion and a proposed triage schema.
    Emerg Radiol
    . 2009;16:115–120.
  • Oltmann SC, Fischer A, Barber R, et al. Pediatric ovarian malignancy presenting as ovarian torsion: Incidence and relevance.
    J Pediatr Surg
    . 2010;45:135–139.
  • Smorgick N, Pansky M, Feingold M, et al. The clinical characteristics and sonographic findings of maternal ovarian torsion in pregnancy.
    Fertil Steril
    . 2009;92:1983–1987.
See Also (Topic, Algorithm, Electronic Media Element)
  • Abdominal Pain
  • Ectopic Pregnancy
  • Endometriosis
  • Pelvic Inflammatory Disease
CODES
ICD9
  • 620.0 Follicular cyst of ovary
  • 620.2 Other and unspecified ovarian cyst
  • 620.5 Torsion of ovary, ovarian pedicle, or fallopian tube
ICD10
  • N83.0 Follicular cyst of ovary
  • N83.20 Unspecified ovarian cysts
  • N83.51 Torsion of ovary and ovarian pedicle
PAGET DISEASE
Anna L. Waterbrook

Matthew C. Kostura
BASICS
DESCRIPTION
  • Paget disease involves resorption of normal bone and its replacement with fibrous and sclerotic tissue
  • Also known as osteitis deformans
  • Usually focal, bones most frequently involved include:
    • Pelvis (70%)
    • Femur (55%)
    • Skull (42%)
    • Tibia (32%)
    • Spine (53%, lumbar spine)
    • Flat bones
  • Usually found incidentally and generally asymptomatic
  • Occurs in ∼1–2% of patients >55 yr old
  • Incidence increases with age
  • Starts with resorptive or osteolytic phase, during which osteoclasts remove healthy bone
  • Hypervascularity begins in resorptive phase:
    • Predisposes to hematoma and fracture
  • Resorbed bone is eventually replaced by irregular, dense, disorganized trabecular bone in sclerotic or osteoplastic phase forming “mosaic pattern”
  • Malignant transformation is rare:
    • Osteosarcoma is malignancy of concern
    • Usually malignant transformation occurs in 1%
  • More common in men
  • More common in European descent
  • Less common in Asian or Scandinavian descent
  • Typically involves 1 bone (monostotic)
  • May involve a few bones (polyostotic)

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