FOLLOW-UP
DISPOSITION
- Adverse outcomes, particularly dysrhythmias, are uncommon but generally occur within 1st 24 hr.
- No single test or combination of tests will accurately predict which patients can be discharged safely from ED:
- All patients in whom diagnosis is seriously being entertained should be admitted to a monitored setting.
Admission Criteria
- EKG abnormalities
- Cardiac enzyme abnormalities
- Hemodynamic instability
- Other studies suggesting cardiac contusion
- Admit to monitored unit for close observation.
Discharge Criteria
Asymptomatic patients with no EKG abnormalities or dysrhythmia and with normal cardiac enzymes after 6–8 hr period may be discharged.
Issues for Referral
Immediate surgical consultation:
- Suspected myocardial wall rupture
- Suspected valve or papillary muscle rupture
- Suspected septal rupture
- Coronary artery thrombosis
- Pericardial effusion
- Cardiac tamponade
FOLLOW-UP RECOMMENDATIONS
Discharged patients:
- Should have follow-up within 24 hr of injury
PEARLS AND PITFALLS
- Obtain EKG in patients following chest wall trauma.
- Perform FAST exam on all patients to assess pericardium.
- External signs of chest wall trauma should increase concern of blunt cardiac injury.
- Pediatric patients may have little or no external signs of chest wall trauma.
- Do not administer thrombolytics to patients with ST elevation MI following trauma.
- Negative troponin I and normal EKG make significant blunt cardiac injury unlikely.
ADDITIONAL READING
- Clancy K, Velopulos C, Bilaniuk JW, et al. Screening for blunt cardiac injury: An Eastern Association for the Surgery of Trauma practice management guideline.
J Trauma Acute Care Surg
. 2012;73:S301–S306.
- El Chami MF, Nicholson W, Helmy T. Blunt cardiac trauma.
J Emerg Med
. 2008;127–133.
- Rajan GP, Zellweger R. Cardiac troponin I as a predictor of arrhythmia and ventricular dysfunction in trauma patients with myocardial contusion.
J Trauma
. 2004;57:801–808.
- Salim A, Velmahos GC, Jindal A, et al. Clinically significant blunt cardiac trauma: Role of serum troponin levels combined with electrocardiographic findings.
J Trauma
. 2001;50:237–243.
- Sybrandy KC, Cramer MJ, Burgersdijk C. Diagnosing cardiac contusion: Old wisdom and new insights.
Heart
. 2003;89(5):485–489.
CODES
ICD9
861.01 Contusion of heart without mention of open wound into thorax
ICD10
- S26.01XA Contusion of heart with hemopericardium, initial encounter
- S26.11XA Contusion of heart without hemopericardium, init encntr
- S26.91XA Contusion of heart, unsp w or w/o hemopericardium, init
MYOCARDITIS
Liudvikas Jagminas
BASICS
DESCRIPTION
- An inflammatory change in the heart muscle characterized by myocyte necrosis and subsequent myocardial destruction
- Direct cytotoxic effect of causative agent followed by a secondary immune response
- True incidence is unknown because many cases are asymptomatic.
- Autopsy studies have demonstrated evidence of myocarditis in 1–7% of cases and >50% in HIV patients.
- Male > female (1.5:1)
- Average age of patients with myocarditis is 42 yr.
- Major cause of unexpected sudden death (15–20% of cases) <40 yr old
ETIOLOGY
- Viral:
- Enteroviruses (coxsackie B)
- Adenovirus
- Herpesvirus (including cytomegalovirus [CMV])
- Hepatitis C
- Influenza
- Echovirus
- Herpes simplex virus
- Varicella-zoster
- Epstein–Barr virus
- Cytomegalovirus
- Mumps
- Rubeola
- Variola/vaccinia
- Yellow fever
- Rabies
- HIV
- Bacteria:
- Diphtheria
- Tuberculosis
- Brucellosis
- Psittacosis
- Meningococcus
- Mycoplasma
- Group A streptococcus
- Protozoa:
- Leishmaniasis
- Malaria
- Toxoplasmosis in the immunocompromised host
- Treponema cruzi
(Chagas disease):
- Most common cause of heart failure and myocarditis worldwide
- 20 million persons infected in Central and South America
- Trichinosis
- Trypanosomiasis
- Spirochetes:
- Borrelia burgdorferi,
the spirochete agent in Lyme disease
- Syphilis
- Rickettsial:
- Scrub typhus
- Rocky Mountain spotted fever
- Q fever
- Fungal:
- Candidiasis
- Aspergillosis
- Cryptococcosis
- Histoplasmosis
- Actinomycosis
- Helminthic
- Trichinosis
- Echinococcosis
- Schistosomiasis
- Cysticercosis
- Drugs:
- Acetaminophen
- Ampicillin
- Chemotherapeutic agents (anthracyclines)
- Cocaine
- Hydrochlorothiazide
- Lithium
- Methyldopa
- Penicillin
- Sulfamethoxazole
- Sulfonamides
- Zidovudine
- Radiation
- Hypersensitivity
- Heavy metals
- Hydrocarbons
- Carbon monoxide
- Arsenic
- Autoimmune disorders:
- Systemic lupus erythematosus (SLE)
- Wegener granulomatosis
- Kawasaki disease
- Giant cell arteritis
- Sarcoidosis
- Peripartum cardiomyopathy
- Bites/stings:
- Scorpion
- Snake
- Black widow venom
DIAGNOSIS
SIGNS AND SYMPTOMS
Arrhythmias (18%), dyspnea (72%), and chest pain (35%)
History
- Fatigue
- Myalgias/arthralgias
- Malaise
- Fever
- Chest pain:
- Reported in 35%
- Most commonly pleuritic, sharp, stabbing, precordial
- Dyspnea on exertion is common.
- Orthopnea and shortness of breath if congestive heart failure (CHF) is present
- Palpitations are common
- Acute coronary syndrome due to local spasm & inflammation
- Syncope:
- May signal high-grade aortic valve block or risk for sudden death from VT/VF
Physical-Exam
- Fever
- Tachypnea
- Tachycardia:
- Often out of proportion to fever
- Cyanosis
- Hypotension:
- Due to left ventricular dysfunction
- Uncommon in the acute setting and indicates a poor prognosis when present
- Bibasilar crackles
- Rales
- Jugular venous distention (JVD)
- Peripheral edema
- Hepatomegaly
- Ascites
- S
3
or a summation gallop if significant biventricular involvement
- Intensity of S
1
may be diminished
- Murmurs of mitral or tricuspid regurgitation
- Pericardial friction rub if associated with pericarditis
Pediatric Considerations
- Most common cause of heart failure in previously healthy children
- Particularly infants, present with nonspecific symptoms:
- Fever
- Respiratory distress
- Poor feeding or, in cases with CHF, sweating while feeding
- New onset murmur
- Cyanosis in severe cases
ESSENTIAL WORKUP
DIAGNOSIS TESTS & NTERPRETATION
Lab
- Cardiac enzymes
- Troponin T: Low levels can be used to exclude myocarditis
- Troponin I specificity is 89%; sensitivity is 34%
- Creatinine kinase (elevated MB) may be elevated from myocardial necrosis
- Erythrocyte sedimentation rate (ESR) is elevated in 60% during the acute phase.
- Leukocytosis is present in 25%.
- Viral titers; cultures rarely positive
- Mycoplasma, antistreptolysin titers, cold agglutinin titer
- Hepatitis panels
- Lyme titer
- Monospot testing
- CMV serology
- Blood cultures