EKG:
- Prolonged QT (most common)
- Nonspecific ST changes
- Premature ventricular contractions
- Atrial fibrillation
- Ventricular tachycardia
- Acute MI (rare)
DIFFERENTIAL DIAGNOSIS
Other causes of coma, cardiac dysrhythmias, or trauma:
- Hypoglycemia
- Intoxication
- Drug overdose
- Cardiovascular disease
- Cerebrovascular accident
- Seizure
- Syncope
TREATMENT
PRE HOSPITAL
- Field triage should rapidly focus on providing ventilatory support to unconscious victims or those in cardiopulmonary arrest:
- Prevents primary cardiac arrest from degenerating into hypoxia-induced secondary cardiac arrest
- Conscious victims are at lower risk for imminent demise.
- Spine immobilization for:
- Cardiopulmonary arrest (suspected trauma)
- Significant mechanical trauma
- Suspected loss of consciousness at any time
- Cover superficial burns with sterile saline dressings.
- Immobilize injured extremities.
- Rapid extrication to decrease risk for repeat lightning strikes
INITIAL STABILIZATION/THERAPY
- ABCs
- Standard advanced cardiac life support measures for cardiac arrest
- Diligent primary and secondary survey for traumatic injuries and other causes of collapse/injury:
- Maintain cervical spine precautions until cleared.
- Treat altered mental status with glucose, naloxone, or thiamine as indicated.
- Hypotension requires volume expansion, blood products, and/or pressor agents.
ED TREATMENT/PROCEDURES
- IV access
- Cardiac monitor and pulse oximetry
- Clean and dress burns.
- Tetanus prophylaxis
- Treat myoglobinuria if present:
- Diuretics, such as furosemide or mannitol
- Alkalinize urine to a pH of 7.45 with IV sodium bicarbonate
- Volume expansion:
- Do not follow burn treatment formulas because lightning burns are rarely the cause of fluid loss.
- Occult deep burn injury is rare when compared with other types of electrical current injury.
- Titrate volume administration to urine output.
- Fluid loading may be dangerous if patient has concomitant head injury.
- Compartment syndrome:
- Must be distinguished from vasospasm, autonomic dysfunction, and paralysis, which are usually self-limited phenomena.
- Fasciotomy will rarely be necessary.
- NSAIDs and high-dose steroids have been proposed to reduce long-term neurologic and corneal damage.
MEDICATION
- Furosemide: 1 mg/kg IV slow bolus q6h
- Mannitol: 0.5 mg/kg IV, repeat PRN
- Sodium bicarbonate: 1 amp IV push (peds: 1 mEq/kg) followed by 2–3 amps/L D5W IV fluid
FOLLOW-UP
DISPOSITION
Admission Criteria
- Postcardiac arrest patients
- History of change in mental status/altered level of consciousness
- History of chest pain, dysrhythmias, or ECG changes:
- May not resolve spontaneously
- 24–48 hr observation period to identify potentially unstable cases
- Myoglobinuria
- Acidosis
- Extremity injury with or at risk for compartment syndrome
Discharge Criteria
Asymptomatic patients with no injuries
FOLLOW-UP RECOMMENDATIONS
- Close follow-up with subspecialists may be required due to the risk for delayed sequelae:
- Neurology:
- Memory deficit
- Attention deficit
- Aphasia
- Sleep disturbance
- Prolonged paresthesia and dysesthesias
- Ophthalmology
- ENT
- Psychology/psychiatry:
- Anxiety
- Depression
- Personality changes
- Post-traumatic stress disorder
PEARLS AND PITFALLS
- Do not follow burn treatment formulas for lightning burns and injuries.
- Be diligent in the primary and secondary survey so as not to miss occult injuries.
- Have a low threshold to admit and monitor patients with cardiopulmonary complaints, as unstable dysrhythmias may occur 24–48 hr post injury.
ADDITIONAL READING
- Cooper MA, Andrews CJ, Holle RL. Lightning injuries. In: Auerbach PS, ed.
Wilderness Medicine
. 5th ed. St. Louis, MO: Mosby; 2007:67–108.
- Cooper MA, Holle RL. Mechanisms of lightning injury should affect lightning safety messages. 21st International Lightning Detection Conference. April 19–20, 2010; Orlando, FL.
- O’Keefe Gatewood M, Zane RD. Lightning injuries.
Emerg Med Clin North Am
. 2004;22(2):369–403.
- Price T, Cooper MA. Electrical and lightning injuries. In: Marx JA, Hockenberger RS, Walls RM, et al., eds.
Rosen’s Emergency Medicine
. 6th ed. Philadelphia, PA: Mosby; 2006.
See Also (Topic, Algorithm, Electronic Media Element)
Electrical Injury
CODES
ICD9
- 949.0 Burn of unspecified site, unspecified degree
- 994.0 Effects of lightning
- 994.8 Electrocution and nonfatal effects of electric current
ICD10
- T30.0 Burn of unspecified body region, unspecified degree
- T75.00XA Unspecified effects of lightning, initial encounter
- T75.09XA Other effects of lightning, initial encounter
LITHIUM POISONING
Sean M. Bryant
BASICS
DESCRIPTION
- GI absorption is rapid:
- Regular release: Peak serum levels 2–4 hr
- Sustained release: Peak serum levels 4–12 hr
- Half-life 24 hr
- Slow distribution (at least 6 hr)
- Volume of distribution 0.6–0.9 L/kg
- Elimination:
- Not
metabolized
- Renal excretion (unchanged)
- Reabsorbed in the
proximal
tubules by sodium transport mechanism
- Elimination half-life (therapeutic) is 20–24 hr and prolonged in chronic users
- Therapeutic and toxic indices:
- Therapeutic and toxic effects occur
only
when lithium is intracellular
- Narrow toxic-to-therapeutic ratio
- Therapeutic level 0.6–1.2 mEq/L (postdistribution)
- Because of small size, renal handling is similar to sodium, potassium, and magnesium
- Risk factors:
- Acute conditions increasing risk of toxicity:
- Dehydration (larger percent reabsorbed)
- Overdose
- Chronic conditions:
- Hypertension
- Diabetes mellitus
- Renal failure
- Congestive heart failure
- Advanced age
- Dose change
- Drug interactions
- Lithium therapy
- Low-salt diet
- The following may result in increased serum lithium levels due to decreased renal clearance or exacerbated effects:
- NSAIDs
- Thiazide diuretics
- ACE inhibitors
- Phenytoin
- Tricyclic antidepressants
- Phenothiazines
ETIOLOGY
- Acute or chronic conditions affecting lithium clearance
- Overdose
DIAGNOSIS