DIFFERENTIAL DIAGNOSIS
- Left-sided CHF:
- Acute exacerbation of COPD
- Asthma exacerbation
- Acute respiratory distress syndrome
- Pneumonia, bronchitis
- Constrictive pericarditis
- Anemia, malnutrition
- Pericardial tamponade
- Coarctation of aorta
- Right-sided HF:
- Nephrotic syndrome, chronic renal failure
- Cirrhosis
- Left-side heart failure
- Pulmonary embolism
- Sleep disordered breathing
- Venous stasis
TREATMENT
PRE HOSPITAL
- IV access
- Supplemental oxygen
- Cardiac monitor and pulse oximetry
- EKG
- Sublingual nitrates for active chest pain without hypotension
- Furosemide
- Endotracheal intubation may be required.
INITIAL STABILIZATION/THERAPY
- IV access
- Supplemental oxygen
- Cardiac monitor and pulse oximetry
- EKG
- Elevate head of bed to reduce venous return.
- Control airway as needed:
- Noninvasive positive pressure ventilation
- CPAP vs. BiPAP
- Reduce work of breathing, improve oxygenation, decrease need for intubation, possible mortality benefit
- Some studies report higher incidence of MI with BiPAP over CPAP in acute CHF; studies not conclusive
- Intubation for impending respiratory failure
ED TREATMENT/PROCEDURES
- General: Oxygenate, ventilate, treat underlying condition when possible
- Congestion with adequate perfusion: Reduce preload, consider fluid restriction
- Rapidly reduce preload in acute pulmonary edema:
- Sublingual or IV nitroglycerin
- Nitro paste
- IV diuretics (less rapid/effective in patients with poor renal perfusion)
- Avoid preload reduction in ADHF when suspected etiology is aortic stenosis, HOCM, or pulmonary hypertension.
- Cautious afterload reduction in ADHF: Avoid ACEi and ARBs in cases of hypotension, acute renal failure, and hyperkalemia.
- Limited benefit, may cause hypotension
- Poor perfusion with hypotension:
- Agents that increase contractility:
- Dobutamine
- Dopamine
- Milrinone
- Avoid vasodilators (nitrates, morphine)
- Initiate diuretics after inotropes.
- Initiate venous thromboembolism prophylaxis in those with ADHF without contraindications
Pediatric Considerations
- Neonates (1st weeks of life):
- Suspect ductal-dependent cardiac lesions if clinical CHF and no improvement with O
2
:
- PGE1 to maintain patent ductus
- Children:
- IV furosemide, and dopamine or milrinone
- IV nitroglycerin for pulmonary edema
MEDICATION
- Aspirin: 325 mg PO/PR if AMI is suspected
- Bumetanide (Bumex): 1–3 mg IV, max. 10 mg/day
- Dobutamine: 2–10 μg/kg/min IV, max. of 40 μg/kg/min
- Dopamine: 2–20 μg/kg/min IV, max. of 50 μg/kg/min
- Enalapril: 0.625–1.25 mg IV; 2.5–20 mg/d PO
- Furosemide (Lasix): No prior use: 40 mg IVP; prior use: Double 24-hr dose (80–180 mg IV); no effect in 30 min: Redouble dose
- Milrinone: 50 μg/kg IV load; 0.375–0.75 μg/kg/min IV
- Nesiritide: 2 μg/kg bolus, then infusion of 0.01 μg/kg/min
- Nitroglycerin: 0.4 mg sublingual; 1–2 in of nitro paste; 5–20 μg/min IV, max. of 100–200 μg/min IV. USE NON-PVC tubing.
- Nitroprusside: 0.3–10 μg/kg/min IV (starting dose), max. of 10 μg/kg/min
Pregnancy Considerations
ACEi and ARBs are associated with multiple fetal abnormalities and should be held
- Oxygen
- Nitroglycerin
- Furosemide
FOLLOW-UP
DISPOSITION
Admission Criteria
- ICU:
- Pulmonary edema
- Cardiogenic shock
- Concomitant MI or ischemia
- Medical wards:
- New-onset CHF
- Symptoms not relieved by ED therapy
Discharge Criteria
- Mild exacerbation of chronic CHF:
- Responds to ED treatment
- No other cardiac and pulmonary findings
- Close follow-up should be arranged with continuation of diuretic, vasodilator, or ACE inhibitor therapy and patient lifestyle education.
Issues for Referral
Consider ICD and/or BV pacer in advanced HF
- Shown to decrease mortality and hospitalization rates in select patient groups
FOLLOW-UP RECOMMENDATIONS
- Close follow-up within 1 wk of discharge
- Medication and dietary compliance
- Frequent home monitoring of body weight
- Monitor electrolytes and renal function during chronic diuretic therapy
PEARLS AND PITFALLS
- BNP may be useful if CHF diagnosis uncertain.
- In severe CHF, NIPPV can improve impending respiratory compromise.
- Be vigilant in searching for and treating the underlying cause of the heart failure exacerbation (e.g., MI, PE, valvular pathology).
ADDITIONAL READING
- Heart Failure Society of America. Executive summary: HFSA 2010 Comprehensive Heart Failure Practice Guideline.
J Card Fail
. 2010;16(6):475–535.
- Singer AJ, Birkhahn RH, Guss D, et al. Rapid Emergency Department Heart Failure Outpatients Trial (REDHOTII): A randomized controlled trial of the effect of serial B-type natriuretic peptide testing on patient management.
Circ Heart Failure.
2009;2:287–293.
- Silvers SM, Howell JM, Kosowsky JM, et al. ACEP Clinical policy: Critical issues in the evaluation and management of adult patients presenting to the emergency department with acute heart failure syndromes.
Ann Emerg Med
. 2007;49(5):627–669.
CODES
ICD9
- 428.0 Congestive heart failure, unspecified
- 428.20 Systolic heart failure, unspecified
- 428.30 Diastolic heart failure, unspecified
ICD10
- I50.9 Heart failure, unspecified
- I50.20 Unspecified systolic (congestive) heart failure
- I50.30 Unspecified diastolic (congestive) heart failure
CONJUNCTIVITIS
Jessica Freedman
BASICS
DESCRIPTION
Inflammation of the conjunctiva arising from a broad group of etiologies. Commonly referred to as “pink eye.”
ETIOLOGY
- Bacterial:
- Staphylococcus aureus
- Streptococcus pneumoniae
- Haemophilus influenzae
- Gonococcal:
- Chlamydia:
- Transmission occurs via autoinoculation from genital secretions.
- Often occurs in newborns
- Viral:
- Adenovirus most common
- Epidemic keratoconjunctivitis (EKC) is caused by adenovirus subtypes.
- Frequently associated with upper respiratory infections or exposure to someone with a red eye
- Most commonly referred to as “pink eye”
- Herpes simplex virus (HSV)
- Recurrent ocular infection occurs in 25% patients within 2 yr.
- Use of steroids is contraindicated:
- Frequent history of allergy, atopy, nasal symptoms
- Contact related
- May be due to chemical irritation, hypersensitivity from preservatives, medications, shampoo, chlorine, dust, smoke
- Pseudomonas commonly implicated organism:
- May be found in patients using saliva to clean contact lenses
DIAGNOSIS