5. Wait 30–45 sec
6. Intubate when optimal conditions achieved
*Consider pretreatment with fentanyl (1–2 μg/kg) IV push (over 1–2 min) and lidocaine
(1.5 mg/kg) IV push if concern for increased intracranial pressure or severe hypertension
*Consider defasciculating dose of paralytic if concern for increased intracranial pressure (see table for dosage)
*Atropine: 0.02 mg/kg IV push (for children <1 y)
Neuromuscular Blocking Agents
Sedative and Induction Agents
Pediatric Vital Signs and Resuscitation Equipment Sizes
Temperature Conversion: Celsius ↔ Fahrenheit
Weight Conversion: Pounds ↔ Kilograms
ABDOMINAL AORTIC ANEURYSM
Daniel J. Henning
•
Jason C. Imperato
•
Carlo L. Rosen
BASICS
DESCRIPTION
- Focal dilation of the aortic wall with an increase in diameter by at least 50% (>3 cm).
- 95% are infrarenal.
- Rapid expansion or rupture causes symptoms.
- Rupture can occur into the intraperitoneal or retroperitoneal spaces
- Intraperitoneal rupture is usually immediately fatal
- Average growth rate of 0.2–0.5 cm/yr
- Of ruptures:
- 90% overall mortality
- 80% mortality for patients who reach the hospital
- 50% mortality for patients who undergo emergency repair
Geriatric Considerations
- Risk increases with advanced age.
- Present in:
- 4–8% of all patients older than 65 yr
- 5–10% of men 65–79 yr old
- 12.5% of men 75–84 yr old
- 5.2% of women 75–84 yr old
ETIOLOGY
- Risk factors:
- Male gender
- Age >65 yr
- Family history
- Cigarette smoking
- Atherosclerosis
- HTN
- Diabetes mellitus
- Connective tissue disorders:
- Ehlers–Danlos syndrome
- Marfan syndrome
- Uncommon causes:
- Blunt abdominal trauma
- Congenital aneurysm
- Infections of the aorta
- Mycotic aneurysm secondary to endocarditis
- Rupture risk factors:
- Size (annual rupture rates):
- Aneurysms 5–5.9 cm = 4%
- Aneurysms 6–6.9 cm = 7%
- Aneurysms 6.9–7 cm = 20%
- Expansion:
- A small aneurysm that grows >0.5 cm in 6 mo is at high risk for rupture.
- Gender:
- For aneurysms 4.0–5.5 cm, women have 4× higher risk of rupture compared to men with similar sized aneurysms.
DIAGNOSIS
SIGNS AND SYMPTOMS
History
- Abdominal, back, or flank pain:
- Vague, dull quality
- Constant, throbbing, or colicky
- Acute, severe, constant
- Radiates to chest, thigh, inguinal area, or scrotum
- Flank pain radiating to the groin in 10% of cases
- Lower extremity pain
- Syncope, near-syncope
- Unruptured are most often asymptomatic
Physical-Exam
- Unruptured:
- Abdominal mass or fullness
- Palpable, nontender, pulsatile mass
- Intact femoral pulses
- Ruptured:
- Classic triad (only 1/3 of the cases):
- Pain
- Hypotension
- Pulsatile abdominal mass
- Systemic:
- Hypotension
- Tachycardia
- Evidence of systemic embolization
- Abdomen:
- Pulsatile, tender abdominal mass
- Flank ecchymosis (Grey Turner sign) indicates retroperitoneal bleed.
- Only 75% of aneurysms >5 cm are palpable.
- Abdominal tenderness
- Abdominal bruit
- GI bleeding
- Extremities:
- Diminished or asymmetric pulses in the lower extremities
- Complications:
- Large emboli: Acute painful lower extremity
- Microemboli: Cool, painful, cyanotic toes (“blue toe syndrome”)
- Aneurysmal thrombosis: Acutely ischemic lower extremity
- Aortoenteric fistula: GI bleeding
ESSENTIAL WORKUP
- Unstable patients:
- Bedside abdominal US
- Explorative surgery without further ancillary studies
- Stable, symptomatic patients:
DIAGNOSIS TESTS & NTERPRETATION
Lab
- Type and cross-match blood
- CBC
- Creatinine
- Urinalysis
- Coagulation studies
Imaging
- Plain radiographs:
- Abdominal or lateral lumbar radiographs
- Only if other tests are unavailable
- Curvilinear calcification of the aortic wall or a paravertebral soft-tissue mass indicates abdominal aortic aneurysm (AAA) in 75% of patients.
- Cannot identify rupture
- Negative study does not rule out AAA.
- Abdominal ultrasound:
- 100% sensitive and 92–99% specific for detecting AAA prior to rupture
- In emergent setting, useful to determine presence of AAA.
- Ultrasound findings consistent with AAA are enlarged aorta >3 cm or focal dilatation of the aorta.
- Sensitivity has been reported as low as 10% following rupture.
- Indicated in the unstable patient
- Abdominal CT scan:
- Contrast is not necessary to make the diagnosis but CT angiogram is required for surgical planning for an endovascular approach
- Will demonstrate both aneurysm and site of rupture (intraperitoneal vs. retroperitoneal)
- Allows more accurate measurement of aortic diameter
DIFFERENTIAL DIAGNOSIS
- Other abdominal arterial aneurysms (i.e., iliac or renal)
- Aortic dissection
- Renal colic
- Biliary colic
- Musculoskeletal back pain
- Pancreatitis
- Cholecystitis
- Appendicitis
- Bowel obstruction
- Perforated viscus
- Mesenteric ischemia
- Diverticulitis
- GI hemorrhage
- Aortic thromboembolism
- Myocardial infarction
- Addisonian crisis
- Sepsis
- Spinal cord compression