Mosby's 2014 Nursing Drug Reference (441 page)

BOOK: Mosby's 2014 Nursing Drug Reference
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Canada only   Side effects:
italics
= common;
bold
= life-threatening   
Nurse Alert

TOPICAL
GLUCOCORTICOIDS

betamethasone (augmented) (Rx)

(bay-ta-meth′a-sone)

Diprolene

desonide (Rx)

(dess′oh-nide)

LoKara, Verdeso Foam

fluocinolone (Rx)

(floo-oh-sin′oh-lone)

Derma-Smoothe/F, Synalar

flurandrenolide (Rx)

(flure-an-dren′oh-lide)

Cordran, Cordran SP, Drenison 1/4
, Drenison Tape

halcinonide (Rx)

(hal-sin′oh-nide)

Halog

ACTION:

Antipruritic, antiinflammatory

USES:

Psoriasis, eczema, contact dermatitis, pruritus; usually reserved for severe dermatoses that have not responded to less potent formulation

CONTRAINDICATIONS:

Hypersensitivity, viral infections, fungal infections

Precautions:
Pregnancy (C)

DOSAGE AND ROUTES
Calculator

• Adult and child:
Apply to affected area

Administer:

• 
Only to affected areas; do not get in eyes

• 
Leaving site uncovered or lightly covered; occlusive dressing is not recommended—systemic absorption may occur

• 
Use only on dermatoses; do not use on weeping, denuded, or infected area

• 
Cleansing before application of product

• 
Continuing treatment for a few days after area has cleared

• 
Store at room temperature

SIDE EFFECTS

INTEG:
Acne, atrophy, epidermal thinning, purpura, striae

NURSING CONSIDERATIONS
Assess:

• 
Temp; if fever develops, product should be discontinued

• 
For systemic absorption, increased temp, inflammation, irritation

Evaluate:

• 
Therapeutic response: absence of severe itching, patches on skin, flaking

Teach patient/family:

• 
To avoid sunlight on affected area, burns may occur

• 
To limit treatment to 14 days

Canada only   Side effects:
italics
= common;
bold
= life-threatening   
Nurse Alert

TOPICAL
ANTIFUNGALS

nystatin (
OTC
)

(nye-stat′in)

Nyamyc, Nystop, Pediaderm, Pedia-dri

selenium (
OTC
)

(see-leen′ee-um)

Dandrex, Selsun, Selsun Blue

terbinafine (
OTC
)

(ter-bin′a-feen)

Lamisil

tolnaftate (
OTC
)

(tole-naf′tate)

Absorbine Athlete’s Foot Cream, Fungi-Guard, Tinactin

undecylenic acid (
OTC
)

(un-deh-sih-len′ik)

ACTION:

Interferes with fungal cell membrane permeability

USES:

Tinea cruris, tinea pedis, diaper rash, minor skin irritations; amphotericin B is used for candida infections

CONTRAINDICATIONS:

Hypersensitivity

Precautions:
Pregnancy (B), breastfeeding, children

DOSAGE AND ROUTES
Calculator

• 
Massage into affected area, surrounding area daily or bid, continue for 7-14 days, not to exceed 4 wk

Administer:

Topical route

• 
To affected area, surrounding area; do not cover with occlusive dressings

• 
Store below 86° F (30° C)

SIDE EFFECTS

INTEG:
Burning, stinging, dryness, itching, local irritation

NURSING CONSIDERATIONS
Assess:

• 
Skin for fungal infections; peeling, dryness, itching before and throughout treatment

• 
For continuing infection; increased size, number of lesions

Evaluate:

• 
Therapeutic response: decrease in size, number of lesions

Teach patient/family:

• 
To apply with glove to prevent further infection; not to cover with occlusive dressings

• 
That long-term therapy may be needed to clear infection (2 wk-6 mo depending on organism); compliance is needed even after feeling better

• 
Proper hygiene; hand-washing technique, nail care, use of concomitant top agents if prescribed

• 
To avoid use of OTC creams, ointments, lotions unless directed by prescriber

• 
To use medical asepsis (hand washing) before, after each application; to change socks and shoes once a day during treatment of tinea pedis

• 
To report to health care prescriber if infection persists or recurs; if blisters, burning, oozing, swelling occur

• 
To avoid alcohol because nausea, vomiting, hypertension may occur

• 
To use sunscreen or avoid direct sunlight to prevent photosensitivity

• 
To notify health care provider of sore throat, fever, skin rash, which may indicate overgrowth of organisms

Canada only   Side effects:
italics
= common;
bold
= life-threatening   
Nurse Alert

TOPICAL
ANTIINFECTIVES

bacitracin (
OTC
)

(bass-i-tray′sin)

mafenide (Rx)

(ma′fe-nide)

Sulfamylon

salicylic acid (Rx)

(sal′i-sil′ik)

silver sulfADIAZINE (Rx)

(sul-fa-dye′a-zeen)

Flamazine
, Silvadene, SSD, SSD AF, Thermazene

tretinoin (Rx)

(treh′tih-noyn)

Atralin, Avita, Retin-A, Renova

ACTION:

Interferes with bacterial protein synthesis

USES:

Skin infections, minor burns, wounds, skin grafts, primary pyodermas, otitis externa

CONTRAINDICATIONS:

Hypersensitivity, large areas, burns, ulcerations

Precautions:
Pregnancy (C), breastfeeding, impaired renal function, external ear or perforated eardrum

Administer:

• 
Enough medication to cover lesions completely

• 
After cleansing with soap, water before each application; dry well

• 
To less than 20% of body surface area when patient has impaired renal function

SIDE EFFECTS

INTEG:
Rash, urticaria, scaling, redness

NURSING CONSIDERATIONS
Assess:

• 
Allergic reaction: burning, stinging, swelling, redness

• 
For signs of nephrotoxicity or ototoxicity

Perform/provide:

• 
Storage at room temperature in dry place

Evaluate:

• 
Therapeutic response: decrease in size, number of lesions

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