Keto Clarity: Your Definitive Guide to the Benefits of a Low-Carb, High-Fat Diet (65 page)

– Dr. Bill Lagakos

Scientific Studies

General

Boling, C. L., E. C. Westman, W. S. Yancy Jr. “Carbohydrate-Restricted Diets for Obesity and Related Diseases: An Update.”
Current Atherosclerosis Reports
11.6 (2008): 462-9.

Cahill, G. F., Jr. “Fuel Metabolism in Starvation.”
Annual Review of Nutrition
26 (2006): 1-22.

Feinman, R. D., M. Makowske. “Metabolic Syndrome and Low-Carbohydrate Ketogenic Diets in the Medical School Biochemistry Curriculum.”
Metabolic Syndrome and Related Disorders
1.3 (2003): 189-197.

Liu, Y. M. “Medium-Chain Triglyceride (MCT) Ketogenic Therapy.”
Epilepsia
49.Suppl 8 (2008): 33-6.

Manninen, A. H. “Is a Calorie Really a Calorie? Metabolic Advantage of Low-Carbohydrate Diets.”
Journal of the International Society of Sports Nutrition
1.2 (2004): 21-6.

McClernon, F. J., et al. “The Effects of a Low-Carbohydrate Ketogenic Diet and a Low-Fat Diet on Mood, Hunger, and Other Self-Reported Symptoms.”
Obesity
(Silver Spring) 15.1 (2007): 182-7.

Paoli, A., A. Rubini, J. S. Volek, K. A. Grimaldi. “Beyond Weight Loss: A Review of the Therapeutic Uses of Very-Low-Carbohydrate (Ketogenic) Diets.”
European Journal of Clinical Nutrition
67 (2013): 789–796.

Veech, R. L. “The Therapeutic Implications of Ketone Bodies: The Effects of Ketone Bodies in Pathological Conditions: Ketosis, Ketogenic Diet, Redox States, Insulin Resistance, and Mitochondrial Metabolism.”
Prostaglandins, Leukotrienes and Essential Fatty Acids
70.3 (2004): 309-19.

Veech, R. L., et al. “Ketone Bodies, Potential Therapeutic Uses.”
IUBMB Life
51 (2001): 241-7.

Volek, J. S., C. E. Forsythe. “The Case for Not Restricting Saturated Fat on a Low Carbohydrate Diet.”
Nutrition & Metabolism
2 (2005) :21.

Volek, J. S., C. E. Forsythe. “Very-Low-Carbohydrate Diets.” In
Essentials of Sports Nutrition and Supplements,
edited by Jose Antonio, Douglas Kalman, Jeffrey R. Stout, Mike Greenwood, Darryn S. Willoughby, and G. Gregory Haff, 581-604. Totowa, NJ: Humana Press, 2008.

Westman, E. C. “A Review of Very Low Carbohydrate Diets for Weight Loss.”
Journal of Clinical Outcomes Management
6.7 (1999): 36-40.

Westman, E. C. “Is Dietary Carbohydrate Essential for Human Nutrition?”
American Journal of Clinical Nutrition
75.5 (2002): 951-953; author reply 953-954.

Westman, E. C., et al. “Effect of 6-Month Adherence to a Very Low Carbohydrate Diet Program.”
American Journal of Medicine
113.1 (2002): 30-36.

Westman, E. C., et al. “Low-Carbohydrate Nutrition and Metabolism.”
American Journal of Clinical Nutrition
86 (2007): 276-84.

Westman, E. C., J. Mavropoulos, W. S. Yancy Jr., J. S. Volek. “A Review of Low-carbohydrate Ketogenic Diets.”
Current Atherosclerosis Reports
5.6 (2003): 476-483.

Westman, E. C., W. S. Yancy Jr., M. C. Vernon. “Is a Low-Carb, Low-Fat Diet Optimal?”
Archives of Internal Medicine
165.9 (2005): 1071-1072.

Weight Loss/Metabolic Syndrome/Insulin Resistance

Al-Sarraj, T., H. Saadi, J. S. Volek, M. L. Fernandez. “Carbohydrate Restriction Favorably Alters Lipoprotein Metabolism in Emirati Subjects Classified with the Metabolic Syndrome.”
Nutrition, Metabolism & Cardiovascular Disease
20 (2010): 720-726.

Al-Sarraj, T., H. Saadi, J. S. Volek, M. L. Fernandez. “Metabolic Syndrome Prevalence, Dietary Intake, and Cardiovascular Risk Profile among Overweight and Obese Adults 18-50 Years Old from the United Arab Emirates.”
Metabolic Syndrome and Related Disorders
8.1 (2010): 39-46.

Bailey, W. A., E. C. Westman, M. L. Marquart, J. R. Guyton. “Low Glycemic Diet for Weight Loss in Hypertriglyceridemic Patients Attending a Lipid Clinic.”
Journal of Clinical Lipidology
4.6 (2010): 508-14.

Foster, G. D., et al. “A Randomized Trial of a Low-Carbohydrate Diet for Obesity.”
New England Journal of Medicine
348.21 (2003): 2082-2090.

LeCheminant, J. D., et al. “Comparison of a Low Carbohydrate and Low Fat Diet for Weight Maintenance in Overweight or Obese Adults Enrolled in a Clinical Weight Management Program.”
Nutrition Journal
6 (2007): 36.

Noakes, M., P. Foster, J. Keogh, P. Clifton. “Very Low Carbohydrate Diets For Weight Loss And Cardiovascular Risk.”
Asia Pacific Journal of Clinical Nutrition
13.Suppl (2004): S64.

Phelan, S., et al. “Three-Year Weight Change in Successful Weight Losers Who Lost Weight on a Low-Carbohydrate Diet.”
Obesity
(Silver Spring) 15 (2007): 2470–2477.

Ruano, G., et al. “Physiogenomic Analysis of Weight Loss Induced by Dietary Carbohydrate Restriction.”
Nutrition & Metabolism
3 (2006): 20.

Shai, I., et al. “Weight Loss with a Low-Carbohydrate, Mediterranean, or Low-Fat Diet.”
New England Journal of Medicine
359 (2008): 229-241.

Sharman, M. J., J. S. Volek. “Weight Loss Leads to Reductions in Inflammatory Biomarkers after a Very-Low Carbohydrate Diet and a Low-Fat Diet in Overweight Men.”
Clinical Science
107.4 (2004): 365-369.

Sumithran, P., et al. “Ketosis and Appetite-Mediating Nutrients and Hormones after Weight Loss.”
European Journal of Clinical Nutrition
67.7 (2013): 759-64.

Tay, J., et al. “Metabolic Effects of Weight Loss on a Very-Low-Carbohydrate Diet Compared with an Isocaloric High-Carbohydrate Diet in Abdominally Obese Subjects.”
Journal of the American College of Cardiology
51.1 (2008): 59-67.

Vernon, M. C., et al. “Clinical Experience of a Carbohydrate-Restricted Diet for the Metabolic Syndrome.”
Metabolic Syndrome and Related Disorders
2.3 (2004): 180-6.

Volek, J. S., E. C. Westman. “Very-Low-Carbohydrate Weight-Loss Diets Revisited.”
Cleveland Clinic Journal of Medicine
69.11 (2002): 849, 853, 856-848 passim.

Volek, J. S., et al. “Body Composition and Hormonal Responses to a Carbohydrate-Restricted Diet.”
Metabolism
51.7 (2002): 864-870.

Volek, J. S., et al. “Carbohydrate Restriction Has a More Favorable Impact on the Metabolic Syndrome than a Low Fat Diet.”
Lipids
44.4 (2009): 297-309.

Volek, J. S., et al. “Comparison of Energy-Restricted Very Low-Carbohydrate and Low-Fat Diets on Weight Loss and Body Composition in Overweight Men and Women.”
Nutrition & Metabolism
1.1 (2004): 13.

Volek, J. S., R. D. Feinman. “Carbohydrate Restriction Improves the Features of Metabolic Syndrome. Metabolic Syndrome May Be Defined by the Response to Carbohydrate Restriction.”
Nutrition & Metabolism
2 (2005): 31.

Westman, E. C. “A Review of Very Low Carbohydrate Diets for Weight Loss.”
Journal of Clinical Outcomes Management
6.7 (1999): 36-40.

Westman, E. C., et al. “Effect of 6-month Adherence to a Very Low Carbohydrate Diet Program.”
American Journal of Medicine
113.1 (2002): 30-36.

Westman, E. C., W. S. Yancy Jr., M. D. Haub, J. S. Volek. “Insulin Resistance from a Low Carbohydrate, High Fat Diet Perspective.”
Metabolic Syndrome and Related Disorders
3.1 (2005): 14-18.

Yancy, W. S., Jr., et al. “Effects of Two Weight-Loss Diets on Health-Related Quality of Life.”
Quality of Life Research
18.3 (2009): 281-289.

Yancy, W. S., Jr., et al. “A Randomized Trial of a Low-Carbohydrate Diet vs Orlistat Plus a Low-Fat Diet for Weight Loss.”
Archives of Internal Medicine
170.2 (2010): 136-145.

Gastrointestinal Diseases/IBS/GERD/NAFLD

Austin, G. L., et al. “A Very Low Carbohydrate Diet Improves Gastroesophageal Reflux and Its Symptoms.”
Digestive Diseases and Sciences
51.8 (2006): 1307-1312.

Austin, G. L., et al. “A Very-Low-Carbohydrate Diet Improves Symptoms and Quality of Life in Diarrhea-Predominant Irritable Bowel Syndrome.”
Clinical Gastroenterology and Hepatology
7.6 (2009): 706-708.

Tendler, D., et al. “The Effect of a Low-Carbohydrate, Ketogenic Diet on Nonalcoholic Fatty Liver Disease: A Pilot Study.”
Digestive Diseases and Sciences
52.2 (2007): 589-93.

Yancy, W. S., Jr., D. Provenzale, E. C. Westman. “Improvement of Gastroesophageal Reflux Disease after Initiation of a Low-Carbohydrate Diet: Five Brief Case Reports.”
Alternative Therapies in Health and Medicine
7.6 (2001): 116-120.

Polycystic Ovary Syndrome (PCOS)

Mavropoulos, J., W. S. Yancy Jr., J. Hepburn, E. C. Westman. “The Effects of a Low-Carbohydrate, Ketogenic Diet on the Polycystic Ovary Syndrome: A Pilot Study.”
Nutrition & Metabolism
2 (2005): 35.

Epilepsy

Barañano, K. W., A. L. Hartman. “The Ketogenic Diet: Uses in Epilepsy and Other Neurologic Illnesses.”
Current Treatment Options in Neurology
10.6 (2008): 410-9.

Dressler, A., et al. “Type 1 Diabetes and Epilepsy: Efficacy and Safety of the Ketogenic Diet.”
Epilepsia
51.6 (2010): 1086–1089.

Greene, A. E., M. T. Todorova, T. N. Seyfried. “Perspectives on the Metabolic Management of Epilepsy through Dietary Reduction of Glucose and Elevation of Ketone Bodies.”
Journal of Neurochemistry
86.3 (2003): 529–537.

Peterson, S. J., et al. “Changes in Growth and Seizure Reduction in Children on the Ketogenic Diet as a Treatment for Intractable Epilepsy.”
Journal of the American Dietetic Association
105.5 (2005): 718-25.

Diabetes

Accurso, A., et al. “Dietary Carbohydrate Restriction in Type 2 Diabetes Mellitus and Metabolic Syndrome: Time for a Critical Appraisal.”
Nutrition & Metabolism
5 (2008): 9.

Allen, F. M. “Studies Concerning Diabetes.”
Journal of the American Medical Association
63.11 (1914): 939-943.

Boden, G., et al. “Effect of a Low-Carbohydrate Diet on Appetite, Blood Glucose Levels, and Insulin Resistance in Obese Patients with Type 2 Diabetes.”
Annals of Internal Medicine
142.6 (2005): 403-411.

Brand-Miller, J., S. Hayne, P. Petocz, S. Colagiuri. “Low-Glycemic Index Diets in the Management of Diabetes: A Meta-Analysis of Randomized Controlled Trials.”
Diabetes Care
26.8 (2003): 2261-2267.

Dashti, H. M., et al. “Beneficial Effects of Ketogenic Diet in Obese Diabetic Subjects.”
Molecular and Cellular Biochemistry
302.1 (2007): 249-256.

Feinman, R. D., J. S. Volek. “Carbohydrate Restriction as the Default Treatment for Type 2 Diabetes and Metabolic Syndrome.”
Scandinavian Cardiovascular Journal
42.4 (2008): 256-263.

Feinman, R. D., J. S. Volek, E. Westman. “Dietary Carbohydrate Restriction in the Treatment of Diabetes and Metabolic Syndrome.”
Clinical Nutrition Insight
34.12 (2008): 1-5.

Gannon, M. C., F. Q. Nuttall. “Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People with Type 2 Diabetes.”
Diabetes
53.9 (2004): 2375-2382.

Hussain, T. A., et al. “Effect of Low-Calorie Versus Low-Carbohydrate Ketogenic Diet in Type 2 Diabetes.”
Nutrition
28.10 (2012): 1016-21.

Mobbs, C. V., J. Mastaitis, F. Isoda, M. Poplawski. “Treatment of Diabetes and Diabetic Complications with a Ketogenic Diet.”
Journal of Child Neurology
28.8 (2013): 1009-14.

Nielsen, J. V., E. Joensson. “Low-Carbohydrate Diet in Type 2 Diabetes: Stable Improvement of Bodyweight and Glycemic Control During 44 Months Follow-Up.”
Nutrition & Metabolism
5 (2008): 14.

Nielsen, J. V., E. Jonsson, A. Ivarsson. “A Low Carbohydrate Diet in Type 1 Diabetes: Clinical Experience—A Brief Report.”
Upsala Journal of Medical Sciences
110.3 (2005): 267-273.

Nielsen, J. V., E. Jonsson, A. K. Nilsson. “Lasting Improvement of Hyperglycaemia and Bodyweight: Low-Carbohydrate Diet in Type 2 Diabetes. A Brief Report.”
Upsala Journal of Medical Sciences
110.2 (2005): 179-183.

Nielsen, J. V., P. Westerlund, P. Bygren. “A Low-Carbohydrate Diet May Prevent End-Stage Renal Failure in Type 2 Diabetes. A Case Report.”
Nutrition & Metabolism
3 (2006): 23.

Vernon, M. C., et al. “Clinical Experience of a Carbohydrate-Restricted Diet: Effect on Diabetes Mellitus.”
Metabolic Syndrome and Related Disorders
1.3 (2003): 233-238.

Westman, E. C., et al. “The Effect of a Low-Carbohydrate, Ketogenic Diet Versus a Low-Glycemic Index Diet on Glycemic Control in Type 2 Diabetes Mellitus.”
Nutrition & Metabolism
5 (2008): 36.

Westman, E. C., W. S. Yancy Jr., M. Humphreys. “Dietary Treatment of Diabetes Mellitus in yhe Pre-Insulin Era (1914-1922).”
Perspectives in Biology and Medicine
49.1 (2006): 77-83.